Modified Model Results
Comparing original and enhanced model outcomes
Cell Population Dynamics
Original model: tumor cells rapidly overtake normal cells as immune cells become exhausted
Modified model: combined therapies suppress tumor growth while normal cells recover
Treatment Effects
Checkpoint inhibitors (magenta) and CAR-T cells (cyan) during treatment period (days 30-60)
Nutritional intervention builds up gradually from day 70, reaching equilibrium around day 85
Key Insights
Therapeutic Synergy
Sequential application of immunotherapy followed by nutritional support creates better outcomes than either approach alone
Critical Timing
Early immunotherapy (days 30-60) controls initial tumor growth, while later nutritional support (day 70+) maintains long-term health
Clinical Relevance
Model suggests integrating nutritional counseling with standard immunotherapy protocols for improved cancer care